姓名

杜伯雨

出生年月

1976年4月

单位

7790必发集团官网生物医药研究院

所属学科

基础医学-免疫学

职称、职务

教授，生物医药研究院副经理，博士/硕士研究生导师，

E-mail

du.boyu@hotmail.com

研究方向

1.肿瘤发病机制的分子生物学研究

2.肿瘤疾病的靶向治疗

个人简介

杜伯雨，男，1976年4月生，博士，教授，硕士研究生导师，7790必发集团官网生物医药研究院副经理。从事肿瘤疾病发病机制的分子生物学及靶向治疗研究工作。

主持完成科研项目4项，其中国家自然科学基金项目2项，省科技厅面上项目1项。曾在CELL, Cell  death & Disease, Int Immunopharmacol等杂志上发表多篇研究论文。作为发明人获批发明专利多篇，已转让发明专利2项。2017年获评7790必发集团优秀教师。2020年获7790必发集团官网优秀硕士生导师。2021年获十堰市第一届全市职工技术创新成果奖一等奖，并获十堰市五一劳动奖章。

代表作

1. Qiu F, Li Y, Zhu Y, Li G, Lei F,  Zhang S, Luo L, Zhu J, Guo Y, Du B, Xi X*. CX3CR1 might be a promising  predictor of systemic lupus erythematosus patients with pulmonary fibrosis.  Scand J Immunol. 2021 Mar 4:e13038.

2. Xueyan Xi, Yang Guo, Min Zhu, Yuhui  Wei, Gang Li, Boyu Du, Yunfu Wang. Higher expression of monocyte  chemotactic protein 1 in mild COVID-19 patients might be correlated with  inhibition of Type I IFN signaling. Virology Journal. 2021, 18: 12.

3. Xueyan Xi, Yang Guo, Min Zhu, Fen  Qiu, Feifei Lei, Gang Li, Boyu Du. Identification of new potential  antigen recognized by γδT cells in hepatocellular carcinoma. Cancer  Immunology, Immunotherapy. 2021

4. Xu Fan, Min Zhu, Fen Qiu, Wenbo Li,  Minghua Wang, Yang Guo, Xueyan Xi, Boyu Du. Curcumin may be a  potential adjuvant treatment drug for colon cancer by targeting CD44. Int  Immunopharmacol. 2020, 88：106911.

5. Min Zhu, Ye Zhu, Gang Li, Boyu Du,  Xueyan Xi. IFI27 as a potential indicator for severe Enterovirus 71-infected  hand foot and mouth disease.Virus Res. 2020, 28:198149.

6. Li J, Song S, Li X, Zhu J, Li W, Du  B, Guo Y, Xi X, Han R. Down-Regulation of Fibroblast Growth Factor 2  (FGF2) Contributes to the Premature Senescence of Mouse Embryonic Fibroblast.  Med Sci Monit. 2020, 26: e920520.

7. Du B, Zhu M, Li Y, Li G, Xi X.  The prostaglandin E2 increases the production of IL-17 and the expression of  costimulatory molecules on γδ T cells in rheumatoid arthritis. Scand J  Immunol. 2020, 91: e12872.

8. Du B, Fan X, Lei F, Zhang S,  Li G, Xi X. Comparative transcriptome analysis reveals a potential role for  CaMK4 in γδT17 cells from systemic lupus erythematosus patients with lupus  nephritis. Int Immunopharmacol. 2020, 80: 106139.

9. Ling Hao, Boyu Du, Xueyan Xi,  TRIM59 is a novel potential prognostic biomarker in patients with non-small  cell lung cancer: a research based on bioinformatics analysis, Oncology  Letters, 2017, 14:2153-3164.

10. Xi X, Li X, Wu F, Guan X, Jin L, Guo  Y, Song W, Du B. Expression, purification and characterization of  active untagged recombinant human leukemia inhibitory factor from E.coli.  Protein Expr Purif. 2017, 134: 139-146.